丙酮酸脱氢酶激酶同工酶4(PDK4)重组蛋白
英文名称： Recombinant Pyruvate Dehydrogenase Kinase Isozyme 4 (PDK4)
型号:null    产品货号： xy958Mu02
价格:请致电：010-57128832,18610462672
品牌: 中国/美国
试剂级别： 生化级

丙***酸脱氢酶激酶同工酶4(PDK4)重组蛋白 Recombinant Pyruvate Dehydrogenase Kinase Isozyme 4 (PDK4)

FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
Organism species Mus musculus (Mouse)
Product No. xy958Mu02
Source Prokaryotic expression
Host 1NextView more validation data
  • 13700-1-AP;mouse thymus tissuemouse thymus tissue were subjected to SDS PAGE followed by western blot with 13700-1-AP(TBX21,T-bet antibody) at dilution of 1:300
  • 13700-1-AP;mouse thymus tissueIP Result of anti-TBX21,T-bet (IP:13700-1-AP, 4ug; Detection:13700-1-AP 1:300) with mouse thymus tissue lysate 2800ug.
Positive WB detected in Mouse thymus tissue
Positive IP detected in Mouse thymus tissue
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:1000
 TBX21,T-BET 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information TBX21,T-BET 抗体
Immunogen TBX21,T-bet fusion protein ag4618 Full name T-box 21
Calculated molecular
weight		 535aa,58 kDa Observed molecular 
weight		 60-62 kDa
GenBank accession 
number		 BC039739 Gene ID (NCBI) 30009
Gene symbol TBX21 Synonyms T bet, T box 21, T box protein 21, T PET, TBET, TBLYM, TBX21, TBX21,T bet, Transcription factor TBLYM
Background

TBX21 is a transcription factor that drives the Th1 immune response primarily through promoting expression of the IFN-γ gene. TBX21 initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. It has also been shown to play an influential role in inflammatory processes such as inflammatory bowel disease, autoimmune diseases such as rheumatoid arthritis, and immune-mediated conditions like asthma.

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