产品编号HL-0327R

英文名称Rabbit Anti-Bovine IgM

中文名称兔抗牛IgM

别    名Immunoglobulin M.

说 明 书1mg  10mg  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应 cow

产品应用WB=1:1000-5000 ELISA=1:2000-10000 IHC-P=1:200-1000 IHC-F=1:200-1000  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量900kDa

性    状Lyophilized or Liquid

浓    度10mg/1ml

免 疫 原Full length plasma protein

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M PBS(pH7.4)

保存条件Storage: Store at –20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20oC. When reconstituted in sterile distilled water or diluent supplied, theantibody is stable for at least two weeks at 2-4 °C.

产品介绍background:

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to its large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to its high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   

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