Synonyms : | Fibroblast Growth Factor-17, FGFH |
Description : | FGF-17 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through the FGFR 1c, 2c, 3c, and 4. FGF-17 signals induction and patterning of embryonic brain. Recombinant human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues. |
Catalog #: | 100-27 |
Source : | E.coli |
Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Biological Activity : | Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 10.0 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. |
Selected References : | Selected List of References Citing This PeproTech Product |
AA Sequence : | MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT |
PubMed Link : | FGF-17 |
Country of Origin : | USA |
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| Size A | 5μg | $80 | | | Size B | 25μg | $195 | | | Size C | 1mg | $3000 | | |
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| Special Sizes: Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request. |
| Usage: For Research Use Only. Not for use in diagnostic or therapeutic procedures. |