Synonyms : | Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF |
Description : | FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.4 kDa protein consisting of 193 amino acid residues. |
Catalog #: | 100-25 |
Source : | E.coli |
Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Biological Activity : | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. |
Selected References : | Selected List of References Citing This PeproTech Product |
AA Sequence : | MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR |
PubMed Link : | FGF-8 |
Country of Origin : | USA |
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| Size A | 5μg | $80 | | | Size B | 25μg | $195 | | | Size C | 1mg | $3000 | | |
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| Special Sizes: Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request. |
| Usage: For Research Use Only. Not for use in diagnostic or therapeutic procedures. |