Human Growth Factors & Cytokines
Recombinant Human VEGF121


 
		Synonyms :
Vascular Endothelial Growth Factor121, VPF
		Description :
VEGF is a potent growth and angiogenic cytokine.  It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability.  Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis.  VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.  Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates.  Recombinant human VEGF121 is a 28.4 kDa disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains.
		Catalog #:
100-20A
		Source :
E.coli
		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
		Biological Activity :
Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml.
Selected References :
Selected List of References Citing This PeproTech Product
                AA Sequence :
PMAEGGGQNH HEVVKFMDVY QRSYCHPIET LVDIFQEYPD EIEYIFKPSC VPLMRCGGCC NDEGLECVPT EESNITMQIM RIKPHQGQHI GEMSFLQHNK CECRPKKDRA RQENCDKPRR 
		PubMed Link :
VEGF+AND+121
Country of Origin :
USA
        Size A
2μg
$80 
 
 
        Size B
10μg
$195 
 
 
        Size C
1mg
$3900 
 
 
Special                     Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.
Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.