Synonyms : | IL-28A |
Description : | IFN -λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.(Kotenko, SV. et al. Nat Immunology 2003 [1] p. 69-77). Recombinant human IFN-λ 2 is a 19.6 kDa protein containing 174 amino acid residues. |
Catalog #: | 300-02K |
Source : | E.coli |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Biological Activity : | Determined by its ability to activate STAT following receptor-ligand interaction. |
Selected References : | Selected List of References Citing This PeproTech Product |
AA Sequence : | PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV |
PubMed Link : | IFN-lambda-2+AND+human+OR+IL-28A+AND+human |
Country of Origin : | USA |
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| Size A | 5μg | $80 | | | Size B | 20μg | $195 | | | Size C | 1mg | $3000 | | |
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| Special Sizes: Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request. |
| Usage: For Research Use Only. Not for use in diagnostic or therapeutic procedures. |