重组人IL-36 alpha 250ug 英文名称: Recombinant Human IL-36 alpha |
型号:null 产品货号: 200-36A |
价格:请致电:010-57128832,18610462672 |
品牌: 美国 试剂级别: 细胞培养级 |
Recombinant Human IL-36α (IL-1F6)Catalog Number: 200-36A Synonyms: Interleukin-36α, IL36A, Interleukin-1 family member 6 (IL-1F6), FIL1ε (FIL1E), Interleukin-1ε (IL1E) Description: The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8), and γ (IL-1F9). IL-36α is highly expressed in psoriatic plaques, as are IL-36β and IL-36γ, and is the only IL-1 family member found to be expressed by T-cells, as well as monocytes and B-cells. Primarily found in skin and lymphoid tissues, IL-36α is also found to a lesser extent in tissues of the fetal brain, trachea, stomach, and intestine. IL-36α signals through a combination of the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells, and the widely expressed IL-RAcP (IL-1 receptor accessory protein). IL-36α also functions as an agonist of NF-kappaB and MAPK pathways, and induces the production of proinflammatory cytokines and chemokines, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36α is a 17.2 kDa protein containing 154 amino acid residues. AA Sequence: MKIDTPQQGS IQDINHRVWV LQDQTLIAVP RKDRMSPVTI ALISCRHVET LEKDRGNPIY LGLNGLNLCL MCAKVGDQPT LQLKEKDIMD LYNQPEPVKS FLFYHSQSGR NSTFESVAFP GWFIAVSSEG GCPLILTQEL GKANTTDFGL TMLF Source: E.coli 重组人干扰素γ(IFN-γ) 重组人白介素4(IL-4) 重组人白介素12(IL-12) 重组人白介素15(IL-15) 重组人白介素18(IL-18) 重组人白介素-1a(IL-1a) 重组人肿瘤坏死因子(TNFa) 重组人粒巨噬细胞集落刺激因子(GM-CSF) 重组人成纤维细胞生长因子(bFGF) 重组人纤维连接蛋白(Fibronectin) 重组人白蛋白(rHSA) 重组人SCF 重组人FLT3 Ligand OK432 无血清细胞冻存液 PBMC样本密度分离液 AMMS-人间充质干细胞(hMSC)培养基 AMMS-NK细胞无血清培养基 AMMS-DC细胞无血清培养基 AMMS-CIK细胞无血清培养基 其他产品 Gibco AIM-V® CTS™ 无血清细胞培养基 Lonza X-VIVO™ 15无血清细胞培养基 TAKARA GT-T551无血清培养基 TAKARA GT-T551 H3 无血清培养基 CORNING KBM-551培养基 Miltenyi冻存袋 TAKARA GT-T610(A)培养袋 |