Animal-Free Recombinant Human FGF-19

Catalog Number:

AF-100-32

Synonyms:

Fibroblast Growth Factor-19, FGFJ

Description:

The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high-affinity heparin dependent ligand for FGFR4. FGF-19 is expressed during brain development and embryogenesis. Recombinant Human FGF-19 isa 21.8 kDa protein containing 195 amino acid residues. Manufactured using all Animal-Free reagents.

AA Sequence:

MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK

Source:

E.coli

Purity:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED₅₀ for this effect is 100-150 ng/ml.

Research Interests:

	Angiogenesis/ Cardiovascular		Bone, Skeletal, Cartilage
	FGF Superfamily		Proliferation
	Stem Cells & Differentiation

Country of Origin:

USA

Research Use Only. Not for use in diagnostic or therapeutic procedures.