Synonyms : | Liver-Expressed Chemokine, CCL16, NCC-4, HCC-4, LMC, LCC-1, MTN-1 |
Description : | LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines. |
Catalog #: | 300-44 |
Source : | E.coli |
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted LEC is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analysis. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
Biological Activity : | Determined by its ability to chemoattract total human monocytes using a concentration range of 10-100 ng/ml. |
AA Sequence : | QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ |
| Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures. |