PGGT1B,蛋白香叶烯基转移酶1β（FTβ）抗体

产品编号HZ-9548R
英文名称PGGT1B
中文名称蛋白香叶烯基转移酶1β（FTβ）抗体
别 名CAAX farnesyltransferase subunit beta; EC 2.5.1.58; EC=2.5.1.58; Farnesyltransferase; farnesyltransferase CAAX box beta1; farnesyltransferase, CAAX box, beta; FNTB; FNTB_HUMAN; FPTB; FTase beta; FTase-beta; Protein farnesyltransferase subunit beta; RAS proteins prenyltransferase beta; Ras proteins prenyltransferase subunit beta.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
PGGT1B,蛋白香叶烯基转移酶1β（FTβ）抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量49kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human PGGT1B/FNTB
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PGGT1B,蛋白香叶烯基转移酶1β（FTβ）抗体PubMedPubMed
产品介绍background:
Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FT beta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.

Function:
Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.

Subunit:
Heterodimer of an alpha and a beta subunit.

Similarity:
Belongs to the protein prenyltransferase subunit beta family.
Contains 5 PFTB repeats.

Database links:
Entrez Gene: 5229 Human
Omim: 602031 Human
SwissProt: P53609 Human
Unigene: 254006 Human

PGGT1B,蛋白香叶烯基转移酶1β（FTβ）抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.