PCDHAC2,原钙粘蛋白介导的PCDHαC2受体抗体

产品编号HZ-11133R
英文名称PCDHAC2
中文名称原钙粘蛋白介导的PCDHαC2受体抗体
别 名PCDH alpha C2; PCDHAC 2; PCDHAC-2; Protocadherin alpha C2; Protocadherin alpha subfamily C 2; PCDC2_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Goose, Sheep, Chimpanzee,
PCDHAC2,原钙粘蛋白介导的PCDHαC2受体抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量105kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human PCDHAC2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PCDHAC2,原钙粘蛋白介导的PCDHαC2受体抗体PubMedPubMed
产品介绍background:
PCDHAC2 (Protocadherin alpha C2) is a member of the protocadherin family, a subgroup of the cadherin superfamily. Protocadherins are neural cadherin-like cell adhesion proteins that are integral membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific neuronal connections in the brain. PCDHAC2 is one of fifteen tandemly arranged genes within the alpha cluster of protocadherin genes on 5q31.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane. Single-pass type I membrane protein.

Similarity:
Contains 6 cadherin domains.

Gene ID:
56134

Database links:
Entrez Gene: 56134 Human
Entrez Gene: 353237 Mouse
Entrez Gene: 393092 Rat
Omim: 606321 Human
SwissProt: Q9Y5I4 Human
Unigene: 199343 Human
Unigene: 308500 Mouse

PCDHAC2,原钙粘蛋白介导的PCDHαC2受体抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.