CAPZA2,F肌动蛋白α2亚基抗体

产品编号HZ-5128R
英文名称CAPZA2
中文名称F肌动蛋白α2亚基抗体
别 名CAPPA2; CapZ alpha 2; Capping protein (actin filament) muscle Z line, alpha 2; CapZ alpha 2; CAPZ; F actin capping protein subunit alpha 2; CAZA2_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 信号转导 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
CAPZA2,F肌动蛋白α2亚基抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量33kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CapZ alpha 2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CAPZA2,F肌动蛋白α2亚基抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008]

Function:
F-actin-capping proteins bind in a Ca(2+)-independentmanner to the fast growing ends of actin filaments (barbed end)thereby blocking the exchange of subunits at these ends. Unlikeother capping proteins (such as gelsolin and severin), theseproteins do not sever actin filaments.

Subunit:
Heterodimer of an alpha and a beta subunit. Component ofthe WASH complex, composed of F-actin-capping protein subunit alpha(CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta(CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P),FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.Interacts with RCSD1/CAPZIP.

Similarity:
Belongs to the F-actin-capping protein alpha subunitfamily.

CAPZA2,F肌动蛋白α2亚基抗体Database links:
Entrez Gene: 830 Human
Entrez Gene: 493728 Cow
Entrez Gene: 503863 Dog
Entrez Gene: 12343 Mouse
Entrez Gene: 493810 Rat
Omim: 601571 Human
SwissProt: Q5E997 Cow
SwissProt: A0M8V0 Dog
SwissProt: P47755 Human
SwissProt: P47754 Mouse
SwissProt: Q3T1K5 Rat
Unigene: 446123 Human
Unigene: 392504 Mouse
Unigene: 17868 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.