DBNDD2/CK1BP,酪蛋白激酶1结合蛋白抗体

产品编号HZ-14203R
英文名称DBNDD2/CK1BP
中文名称酪蛋白激酶1结合蛋白抗体
别 名C20orf35; Casein kinase-1 binding protein; CK1BP; DBND2_HUMAN; Dbndd2; Dysbindin (dystrobrevin binding protein 1) domain containing 2; Dysbindin domain-containing protein 2; HSMNP1; SCF apoptosis response protein 1.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 激酶和***酸酶
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
DBNDD2/CK1BP,酪蛋白激酶1结合蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量28kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DBNDD2/CK1BP
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DBNDD2/CK1BP,酪蛋白激酶1结合蛋白抗体PubMedPubMed
产品介绍background:
CK1BP is a 261 amino acid member of the dysbindin family and is a paralog of dysbindin, a protein trafficking protein involved in lysosome biosynthesis that has been associated with schizophrenia and muscular dystrophy. Human and rat HSMNP1 share 86% identity and both proteins contain three casein kinase II and PKC (protein kinase C) phosphorylation sites, a putative N-glycosylation site and a PEST motif at the C-terminus. HSMNP1 is a cytoplasmic protein and it specifically localizes to vesicles during the induction of apoptosis. In addition, HSMNP1 may be involved in normal as well as pathological myeloid development. Two isoforms of HSMNP1 exist due to alternative splicing events.

Function:
May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).

Tissue Specificity:
Detected in brain.

Similarity:
Belongs to the dysbindin family.

Gene ID:
55861

DBNDD2/CK1BP,酪蛋白激酶1结合蛋白抗体Database links:
Entrez Gene: 55861 Human
Omim: 611453 Human
SwissProt: Q9BQY9 Human
Unigene: 655055 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.