Caspase-7,半胱胺酸蛋白酶蛋白-7抗体

产品编号HZ-3665R
英文名称Caspase-7
中文名称半胱胺酸蛋白酶蛋白-7抗体
别 名Apoptosis related cysteine peptidase; Apoptosis Related Cysteine Protease; Apoptotic Protease MCH3; CASP 7; CASP7; Caspase7; Caspase 7; CMH 1; CMH1; ICE LAP3; ICE like Apoptotic Protease 3; MCH3.
说 明 书0.1ml 0.2ml
研究领域肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Rabbit,
Caspase-7,半胱胺酸蛋白酶蛋白-7抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量30kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Caspase-7
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Caspase-7,半胱胺酸蛋白酶蛋白-7抗体PubMedPubMed
产品介绍background:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].

The antibody should recognize both pro-form and p20 cleaved-form. The antibody does not cross-react with other Caspase family members.

Caspase-7,半胱胺酸蛋白酶蛋白-7抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Caspase-7（MCH3）—属于胱氨酸-天冬氨酸蛋白酶家族，在凋亡执行阶段起中心作用。 Caspase-7受Caspase-3，-10的剪切活化，在其保守的天冬氨酸处被切成两个片段后聚合成活性酶。