FCAR/CD89,免疫球蛋白A Fc段受体1抗体

产品编号HZ-6586R
英文名称FCAR/CD89
中文名称免疫球蛋白A Fc段受体1抗体
别 名CD89; Fc alpha receptor; FCAR; FCAR_HUMAN; IgA Fc receptor; Immunoglobulin alpha Fc receptor.
说 明 书0.1ml 0.2ml
研究领域免疫学 细胞表面分子 细胞类型标志物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
FCAR/CD89,免疫球蛋白A Fc段受体1抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量29kDa
细胞定位细胞膜 分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FCAR
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FCAR/CD89,免疫球蛋白A Fc段受体1抗体PubMedPubMed
产品介绍background:
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Tissue specificity; Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.

Subunit:
Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2.

Subcellular Location:
Isoform A.1: Cell membrane; Single-pass type I membrane protein.
Isoform A.2: Cell membrane; Single-pass type I membrane protein.
Isoform A.3: Cell membrane; Single-pass type I membrane protein.
Isoform B: Secreted.
Isoform B-delta-S2: Secreted.

FCAR/CD89,免疫球蛋白A Fc段受体1抗体Tissue Specificity:
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.

Similarity:
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Database links:
Entrez Gene: 2204 Human
Omim: 147045 Human
SwissProt: P24071 Human
Unigene: 659872 Human

FCAR/CD89,免疫球蛋白A Fc段受体1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.