Anti-Cytokeratin 8
英文名称： Anti-Cytokeratin 8
型号:null    抗体货号： 26-5098
价格:请致电：010-57128832,18610462672
品牌: 美国/中国    产品商标: american research pr

上海信裕生物科技有限公司是一家集研发、生产、销售、服务于一体的国际领先生物高新技术企业，专营基因、蛋白、抗体、Elisa试剂盒、细胞生物学，分子生物学等高质量生物产品。抗体纯化/标记/免疫检测：免疫分析检测是一项应用广泛的技术，利用抗原和抗体的特异性反应进行检测的一种手段，广泛用于医学病理学、免疫组织化学、分子生物学、生物制药等领域的分析研究与技术测定。制备高特异性、高效价的抗体是实验免疫学技术的基础，抗体质量的高低将直接影响试验的成败。抗体纯化能降低非特异性本底，抗体标记能通过标记物的增强放大效应提高检测灵敏度，采用ELISA、WB、IP、IHC等不同免疫分析技术检测各种样品中特定的目的蛋白。


储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CEACAM7,癌胚抗原相关细胞粘附分子7抗体PubMedPubMed
产品介绍background:
Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEA family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAM7, also referred to as CEA gene-family member 2 (CGM2), is a member of the CEA family that is expressed in normal colorectal epithelia but is downregulated in colorectal cancers, suggesting that it may play a role in tumorigenesis. CECAM7 is expressed on the apical surface of highly differentiated epithelial cells in the colorectal mucosa as well as on isolated ductal epithelial cells within the pancreas. CECAM7 may play an important role in epithelial-microbial interactions. CD66a, a biliary glycoprotein, interacts with CEACAM7.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Strongly down-regulated in colonic adenocarcinomas.

Similarity:
Belongs to the immunoglobulin superfamily. CEA family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene ID:
1087

Database links:
Entrez Gene: 1087 Human
SwissProt: Q14002 Human
Unigene: 74466 Human

CEACAM7,癌胚抗原相关细胞粘附分子7抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.