Anti - CD23
英文名称： Anti - CD23
型号:null    抗体货号： DB 135-0.1
价格:请致电：010-57128832,18610462672
品牌: 美国/中国    产品商标: db biotech

上海信裕生物科技有限公司是一家集研发、生产、销售、服务于一体的国际领先生物高新技术企业，专营基因、蛋白、抗体、Elisa试剂盒、细胞生物学，分子生物学等高质量生物产品。抗体纯化/标记/免疫检测：免疫分析检测是一项应用广泛的技术，利用抗原和抗体的特异性反应进行检测的一种手段，广泛用于医学病理学、免疫组织化学、分子生物学、生物制药等领域的分析研究与技术测定。制备高特异性、高效价的抗体是实验免疫学技术的基础，抗体质量的高低将直接影响试验的成败。抗体纯化能降低非特异性本底，抗体标记能通过标记物的增强放大效应提高检测灵敏度，采用ELISA、WB、IP、IHC等不同免疫分析技术检测各种样品中特定的目的蛋白。

>浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human eRF1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
eRF1,真核肽链释放因子1抗体PubMedPubMed
产品介绍background:
This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X. [provided by RefSeq, Jan 2012].

Function:
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Subunit:
Heterodimer of two subunits, one of which binds GTP. Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.

Subcellular Location:
Cytoplasm.

Tissue Specificity:


DISEASE:


eRF1,真核肽链释放因子1抗体Similarity:
Belongs to the eukaryotic release factor 1 family.

Gene ID:
2107

Database links:
Entrez Gene: 2107 Human
Omim: 600285 Human
SwissProt: P62495 Human
Unigene: 483494 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.