DEFB109,防御素β-109/β-defensin 109抗体

产品编号HZ-14243R
英文名称DEFB109
中文名称防御素β-109/β-defensin 109抗体
别 名Beta defensin 109; DB109_HUMAN; DEFB109 Beta defensin 109; Defensin beta 109.
说 明 书0.1ml 0.2ml
研究领域细胞生物 发育生物学 细菌及病毒
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
DEFB109,防御素β-109/β-defensin 109抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量7.4kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DEFB109
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DEFB109,防御素β-109/β-defensin 109抗体PubMedPubMed
产品介绍background:
Beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. The family of Beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many Beta-defensins also are involved in sperm maturation and capacitation. Beta-defensin 109 is an 87 amino acid secreted protein that is notably expressed on the ocular surface and is found in reduced levels in microbial infection, therefore suggesting that this particular Beta-defensin is unlikely to have a major antimicrobial effect.

Function:
DEFB109 belongs to the beta defensin family. It has antibacterial activity.

Subcellular Location:
Secreted

Similarity:
Belongs to the beta-defensin family.

Gene ID:
641517

DEFB109,防御素β-109/β-defensin 109抗体Database links:
Entrez Gene: 100286963 Human
Entrez Gene: 641517 Human
SwissProt: Q30KR1 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.