ERp57,内质网蛋白57抗体

产品编号HZ-14629R
英文名称ERp57
中文名称内质网蛋白57抗体
别 名58 kDa glucose regulated protein; 58 kDa glucose-regulated protein; 58 kDa microsomal protein; Disulfide isomerase ER 60; Disulfide isomerase ER-60; Endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; ER p57; ER protein 57; ER protein 60; ERp 57; ERp57; ERp60; ERp61; Glucose Regulated Protein 58 Kd; GRP 57; GRP 58; GRP57; GRP58; HsT17083; P58; PDIA 3; PDIA3; PDIA3_HUMAN; Phospholipase C alpha; PI PLC; Protein disulfide isomerase A3; Protein disulfide isomerase family A member 3; Protein disulfide-isomerase A3.
说 明 书0.1ml 0.2ml
研究领域细胞生物 转运蛋白 糖蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Rabbit,
ERp57,内质网蛋白57抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量54kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ERp57
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ERp57,内质网蛋白57抗体PubMedPubMed
产品介绍background:
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq, Jul 2008]

Function:

Subcellular Location:
Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Detected in the flagellum and head region of spermatozoa (at protein level).

Post-translational modifications:

Similarity:
Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains.

Gene ID:
2923

ERp57,内质网蛋白57抗体Database links:
Entrez Gene: 2923 Human
Entrez Gene: 281803 Cow
Entrez Gene: 478279 Dog
Entrez Gene: 14827 Mouse
Entrez Gene: 100156204 Pig
Entrez Gene: 100328685 Rabbit
Entrez Gene: 29468 Rat
Omim: 602046 Human
SwissProt: P38657 Cow
SwissProt: P86235 Hamster
SwissProt: P30101 Human
SwissProt: P27773 Mouse
SwissProt: P11598 Rat
Unigene: 591095 Human
Unigene: 263177 Mouse
Unigene: 11527 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.