Defensin alpha 5,防御素α5抗体

产品编号HZ-10577R
英文名称Defensin alpha 5
中文名称防御素α5抗体
别 名alpha 5; alpha 5 Defensin; DEF5; DEF5_HUMAN; DEF5_RAT; Defa; Defa29; DEFA5; Defcr29; Defcr5; Defensin 5; Defensin alpha 5; Defensin alpha 5 Paneth cell specific; Defensin alpha 5 preproprotein; Defensin; Enteric defensin; HD 5; HD5; HD5(20-94); HD5(63-94); MGC129728; RD 5.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Rat,
Defensin alpha 5,防御素α5抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量4.1kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Defensin alpha 5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Defensin alpha 5,防御素α5抗体PubMedPubMed
产品介绍background:
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.

Function:
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.

Subcellular Location:
Secreted. Cytoplasmic vesicle, secretory vesicle. Peptides HD5(20-94), HD5(23-94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.

Defensin alpha 5,防御素α5抗体Tissue Specificity:
Paneth cells of the small intestine (at protein level).

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the alpha-defensin family.

Gene ID:
1670

Database links:
Entrez Gene: 1670 Human
Omim: 600472 Human
SwissProt: Q01523 Human
Unigene: 655233 Human

Defensin alpha 5,防御素α5抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.