TSPAN13,四分子交联体13抗体

产品编号HZ-9421R
英文名称TSPAN13
中文名称四分子交联体13抗体（四旋蛋白）
别 名NET 6; NET6; Tetraspan NET-6; Tetraspanin-13; TM4SF13; Transmembrane 4 superfamily member 13; Transmembrane 4 superfamily member tetraspan NET 6; Tspan-13; Tspan13; TSN13_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 通道蛋白 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
TSPAN13,四分子交联体13抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human TSPAN13/NET-6
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
TSPAN13,四分子交联体13抗体PubMedPubMed
产品介绍background:
NET-6, also known as TSPAN13 (tetraspanin-13) or TM4SF13 (transmembrane 4 superfamily member 13), is a 204 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission. The gene encoding NET-6 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).

Similarity:
Belongs to the tetraspanin (TM4SF) family.

Gene ID:
27075

Database links:
Entrez Gene: 27075 Human
Entrez Gene: 66109 Mouse
Entrez Gene: 366602 Rat
Omim: 613139 Human
SwissProt: Q3ZBV0 Cow
SwissProt: O95857 Human
SwissProt: Q9D8C2 Mouse
SwissProt: Q5FVL6 Rat
Unigene: 49488 Cow
Unigene: 21306 Dog
Unigene: 364544 Human
Unigene: 254663 Mouse
Unigene: 24284 Rat

TSPAN13,四分子交联体13抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.