Calneuron 1,钙营养蛋白1/钙结合蛋白8抗体

产品编号HZ-12164R
英文名称Calneuron 1
中文名称钙营养蛋白1/钙结合蛋白8抗体
别 名CaBP8; CABP8_HUMAN; Calcium binding protein 8; Calcium binding protein; Calcium binding protein CABP8; Calcium-binding protein 8; Caln1; Calneuron I; Calneuron-1; Calneuron1.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 信号转导 结合蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
Calneuron 1,钙营养蛋白1/钙结合蛋白8抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量25kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Calneuron 1/CABP8
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Calneuron 1,钙营养蛋白1/钙结合蛋白8抗体PubMedPubMed
产品介绍background:
This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

Function:
Negatively regulates Golgi-to-plasma membranetrafficking by interacting with PI4KB and inhibiting its activity(By similarity). May play a role in the physiology of neurons andis potentially important in memory and learning.

Subunit:
Interacts with PI4KB. This binding competes withFREQ/NCS1 binding in a calcium-dependent manner.

Subcellular Location:
Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane.

Tissue Specificity:
Brain specific.

Similarity:
Contains 2 EF-hand domains.

Gene ID:
83698

Calneuron 1,钙营养蛋白1/钙结合蛋白8抗体Database links:
Entrez Gene: 83698 Human
Entrez Gene: 140904 Mouse
Entrez Gene: 363909 Rat
Omim: 607176 Human
SwissProt: Q9BXU9 Human
SwissProt: Q9JJG7 Mouse
SwissProt: Q06BI3 Rat
Unigene: 592750 Human
Unigene: 320206 Mouse
Unigene: 202895 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.