HLX1,同源异型盒基因HLX1蛋白抗体

产品编号HZ-8174R
英文名称HLX1
中文名称同源异型盒基因HLX1蛋白抗体
别 名H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HLX; HLX_HUMAN; Homeobox protein HB24; Homeobox protein HLX1.
说 明 书0.1ml 0.2ml
研究领域细胞生物 转录调节因子 淋巴细胞 t-淋巴细胞 b-淋巴细胞 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
HLX1,同源异型盒基因HLX1蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human HLX1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
HLX1,同源异型盒基因HLX1蛋白抗体PubMedPubMed
产品介绍background:
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.
Tissue specificity:
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.

Function:
Transcription factor required for TBX21/T-bet-dependentmaturation of Th1 cells as well as maintenance of Th1-specific geneexpression. Involved in embryogenesis and hematopoiesis (Bysimilarity).

Subcellular Location:
Nucleus (Potential).

Tissue Specificity:
Low level in normal B and T-cells, high levelin activated lymphocytes and monocytes. Also found in thymus,tonsil, bone marrow, developing vessels, and fetal brain.

Similarity:
Belongs to the H2.0 homeobox family.
Contains 1 homeobox DNA-binding domain.

HLX1,同源异型盒基因HLX1蛋白抗体Database links:
UniProtKB/Swiss-Prot: Q14774.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.