DAZAP2,无精症缺失相关蛋白2抗体

产品编号HZ-14201R
英文名称DAZAP2
中文名称无精症缺失相关蛋白2抗体
别 名DAZ associated protein 2; DAZ-associated protein 2; Dazap2; DAZP2_HUMAN; Deleted in azoospermia associated protein 2; Deleted in azoospermia-associated protein 2.
说 明 书0.1ml 0.2ml
研究领域细胞生物 发育生物学 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
DAZAP2,无精症缺失相关蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量17kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DAZAP2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DAZAP2,无精症缺失相关蛋白2抗体PubMedPubMed
产品介绍background:
This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Function:
DAZAP2 is a proline-rich protein which interacts with RNA binding protiens DAZ and DAZL. It also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. DAZAP2 may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID:
9802

DAZAP2,无精症缺失相关蛋白2抗体Database links:
Entrez Gene: 9802 Human
Omim: 607431 Human
SwissProt: Q15038 Human
Unigene: 369761 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.