HSP27 抗体 (Ser15): Biotin
英文名称： HSP27 Antibody (Ser15): Biotin
型号:null    抗体货号： SPC-1260D-BI
价格:请致电：010-57128832,18610462672
品牌: 加拿大    产品商标: stressmarq

热休克蛋白 25/热休克蛋白 27抗体-兔抗人HSP27 多克隆抗体, 适用物种: 人. 适用应用: WB | IHC

merase II subunit 3; DPOE3_HUMAN; Histone fold protein CHRAC17; HuCHRAC 17; HuCHRAC17; p17; p17 subunit; POL E3; POLE 3; POLE3; Polymerase (DNA directed) epsilon 3; YBL 1;
说 明 书0.1ml 0.2ml
研究领域细胞生物 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse,
DNA Polymerase epsilon,DNA聚合酶ε/DNA pol ε抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量16kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DNA Polymerase epsilon
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNA Polymerase epsilon,DNA聚合酶ε/DNA pol ε抗体PubMedPubMed
产品介绍background:
OLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]

Function:
Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Gene ID:
54107

Database links:
Entrez Gene: 54107 Human
Entrez Gene: 417275 Chicken
Entrez Gene: 510678 Cow
Entrez Gene: 59001 Mouse
Entrez Gene: 100362333 Rat
Entrez Gene: 298098 Rat
Omim: 607267 Human
SwissProt: Q3SZN5 Cow
SwissProt: Q9NRF9 Human
SwissProt: Q9JKP7 Mouse
SwissProt: Q642A5 Rat
Unigene: 108112 Human
Unigene: 27444 Mouse
Unigene: 3290 Rat

DNA Polymerase epsilon,DNA聚合酶ε/DNA pol ε抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.