LRP15,¸»º¬ÁÁ°±ËáÖØ¸´ÐòÁÐLRP15¿¹Ìå
²úÆ·±àºÅHZ-9509R
Ó¢ÎÄÃû³ÆLRP15
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±ð ÃûLRP 15; LRP-15; Leucine rich repeat containing 3B; Leucine-rich repeat protein LRP15; Leucine-rich repeat-containing protein 3B; LRC3B_HUMAN; LRRC3B; MGC102927.
˵ Ã÷ Êé0.1ml 0.2ml
Ñо¿ÁìÓòÖ×Áö ÐÄѪ¹Ü ϸ°ûÉúÎï ÃâÒßѧ Éñ¾ÉúÎïѧ
¿¹ÌåÀ´Ô´Rabbit
¿Ë¡ÀàÐÍPolyclonal
½»²æ·´Ó¦ Human, Mouse, Rat, Cow, Horse, Rabbit,
LRP15,¸»º¬ÁÁ°±ËáÖØ¸´ÐòÁÐLRP15¿¹Ìå²úÆ·Ó¦ÓÃWB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 £¨Ê¯À¯ÇÐÆ¬Ðè×ö¿¹ÔÐÞ¸´£©
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
·Ö ×Ó Á¿25kDa
ϸ°û¶¨Î»Ï¸°ûĤ
ÐÔ ×´Lyophilized or Liquid
Ũ ¶È1mg/1ml
Ãâ Òß ÔKLH conjugated synthetic peptide derived from human LRP15
ÑÇ ÐÍIgG
´¿»¯·½·¨affinity purified by Protein A
´¢ ´æ Òº0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
±£´æÌõ¼þStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
LRP15,¸»º¬ÁÁ°±ËáÖØ¸´ÐòÁÐLRP15¿¹ÌåPubMedPubMed
²úÆ·½éÉÜbackground:
Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers.
Subcellular Location:
Membrane; Single-pass membrane protein (Potential).
Similarity:
Belongs to the LRRC3 family.
Contains 3 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
LRP15,¸»º¬ÁÁ°±ËáÖØ¸´ÐòÁÐLRP15¿¹ÌåDatabase links:
Entrez Gene: 420657 Chicken
Entrez Gene: 116135 Human
Entrez Gene: 218763 Mouse
SwissProt: Q96PB8 Human
SwissProt: Q8VCH9 Mouse
Unigene: 517868 Human
Unigene: 138039 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.