Mitoferrin 1,线粒体铁转运蛋白1抗体
英文名称： Anti-Mitoferrin 1 antibody
型号:null    抗体货号： HZ-9523R
价格:请致电：010-57128832,18610462672
品牌: 中国/美国    产品商标: hzbscience

Mitoferrin 1,线粒体铁转运蛋白1抗体

产品编号HZ-9523R
英文名称Mitoferrin 1
中文名称线粒体铁转运蛋白1抗体
别 名SLC25A37; HT015; MFRN; Mitochondrial iron transporter 1; Mitochondrial solute carrier protein; Mitoferrin1; Mitoferrin-1; MSC; MSCP; predicted protein of HQ2217; PRO1278; PRO1584; PRO2217; Solute carrier family 25 member 37.
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 细胞类型标志物 线粒体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
Mitoferrin 1,线粒体铁转运蛋白1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量37kDa
细胞定位细胞膜 线粒体
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Mitoferrin 1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Mitoferrin 1,线粒体铁转运蛋白1抗体PubMedPubMed
产品介绍background:
Mitoferrin1, SLC25A37, belongs to the mitochondrial carrier family and contains 3 Solcar repeats. It is a mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells and plays an essential role in heme biosynthesis.

Function:
Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.

Subcellular Location:
Mitochondrial inner membrane; Multi-pass membrane protein

Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.

Database links:
Entrez Gene: 51312 Human
Omim: 610387 Human
SwissProt: Q9NYZ2 Human
Unigene: 596025 Human

Mitoferrin 1,线粒体铁转运蛋白1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

minant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.

Desmocollin 2 + 3,桥粒糖蛋白2/桥粒糖蛋白3抗体Similarity:
Contains 5 cadherin domains.

Gene ID:
1824

Database links:
Entrez Gene: 1824 Human
Entrez Gene: 1825 Human
Omim: 125645 Human
Omim: 600271 Human
SwissProt: Q02487 Human
SwissProt: Q14574 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Involvement in disease：Defects in DSC2 are the cause of familial arrhythmogenic right ventricular dysplasia type 11 (ARVD11); also known as arrhythmogenic right ventricular cardiomyopathy 11 (ARVC11). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.