| Catalog Number: 21231 |
| Gene Symbol: BAG1 |
| Description: Anti-Bag1 Rabbit Polyclonal Antibody |
| Background: BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene. It binds to oncogene BCL2, by which enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's. It has been demonstrated that BAG1 and BAG 3 regulate the proteasomal and lysosomal protein elimination pathways, respectively. |
| Immunogen: A synthetic peptide from the central region of Bag1 protein, human origin. |
| Applications: ELISA, WB, IHC |
Recommended Dilutions:
ELISA: 1:500-1:5000
WB: 1:200-1:2000
IHC: 1:20-1:200 |
| Concentration: 0.2 mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purified from serum |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-Bag1 rabbit polyclonal antibody recognizes Bag1 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles. |
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| Western blot: |
