重组人NT-3 (Animal Free) 10ug
英文名称: Recombinant Human NT-3
型号:null    产品货号: AF-450-03
价格:请致电:010-57128832,18610462672
品牌: 美国
试剂级别: 细胞培养级

 

Recombinant Human NT-3

Catalog Number:
AF-450-03
Synonyms:
Neurotrophin-3, Neurotrophic factor, Nerve growth factor-2, NGF-2, HGNF
Description:
NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues).Human and Mouse NT-3 sequences are identical. Manufactured using all non-animal reagents.
AA Sequence:
MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
 
 
 
 
 
 
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.