Recombinant Human FGF-4
 
Catalog Number:
AF-100-31
Synonyms:
Fibroblast Growth Factor-4,  HST-1,  transforming protein KS3,  HBGF-4
Description:
FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues. Manufactured using all non-animal reagents.
AA Sequence:
GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
 
 
 
 
Cross Reactivity:
Mouse
Research Interests:
Angiogenesis/ Cardiovascular
FGF Superfamily
Proliferation
Stem Cells & Differentiation
 
 
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.