Synonyms : | B cell Activating Factor belonging to the TNF family, TNFSF13B, TALL-1, BLys, THANK, zTNF4 |
Description : | BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human soluble BAFF is a 153 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF. |
Catalog #: | 310-13 |
Source : | E.coli |
Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Biological Activity : | Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 μg/ml. |
Selected References : | Selected List of References Citing This PeproTech Product |
AA Sequence : | MAVQGPEETV TQDCLQLIAD SETPTIQKGS YTFVPWLLSF KRGSALEEKE NKILVKETGY FFIYGQVLYT DKTYAMGHLI QRKKVHVFGD ELSLVTLFRC IQNMPETLPN NSCYSAGIAK LEEGDELQLA IPRENAQISL DGDVTFFGAL KLL |
PubMed Link : | BAFF+AND+TNF |
Country of Origin : | USA |
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| | Size A | 5μg | $80 |  | | | | Size B | 20μg | $195 | | | | | Size C | 1mg | $5200 | | | |
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| Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request. |
| Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures. |
