Synonyms : | Immune Interferon, type II interferon, T cell interferon, MAF |
Description : | IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-gamma is a 15.6 kDa protein containing 135 amino acid residues. |
Catalog #: | 400-20 |
Source : | E.coli |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (IEU/μg). |
Biological Activity : | The ED50 as determined by a cytopathic affect inhibition assay with murine L929 cells challenged with EMC virus was < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107 units/mg. |
Selected References : | Selected List of References Citing This PeproTech Product |
AA Sequence : | MQGTLIESLE SLKNYFNSSS MDAMEGKSLL LDIWRNWQKD GNTKILESQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT NFFSNSKAKK DAFMSIAKFE VNNPQIQHKA VNELIRVIHQ LSPESSLRKR KRSRC |
PubMed Link : | IFN-gamma+AND+rat |
Country of Origin : | USA |
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| | Size A | 20μg | $80 |  | | | | Size B | 100μg | $195 | | | | | Size C | 1mg | $1100 | | | |
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| Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request. |
| Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures. |
