Recombinant Human MCP-1 (CCL2)
 
Catalog Number:
AF-300-04
Synonyms:
Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine)
Description:
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Manufactured using all non-animal reagents.
AA Sequence:
QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
 
 
 
 
Cross Reactivity:
Bacteria, Chicken, Monkey, Mouse, Rat
Research Interests:
Angiogenesis/ Cardiovascular
Cancer
Chemotaxis
Immune System
Inflammation
Neurobiology
Wound Healing
Allergy
 
 
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.