Description		Monoclonal Antibody against Class II Beta Tubulin, Clone 6B1
Intended Use		**Research Use Only (RUO)** This product is sold for laboratory research use only, not for human or in-vivo use.
Clone		6B1
Form		Purified Antibody
Host		Mouse
Species Reactivity		Mammalian
IsoType		IgG3
[Ab]		1 mg/mL
Specificity		Tubulin is a major component of microtubules. It exists as a heterodimer consiting of an alpha and a beta subunit. Class II beta tubulin is the major form of tubulin beta in neurons, although it is not neuronal specific and is found in many other tissues including lung tissue and Schwann cells. This antibody was raised against the synthetic peptide CEEEEGEDEA found at the c-terminus of beta II tubulin.
Uses		This antibody is effective in immunoblotting and immunofluorescence (IF).
Suggested Working Dilution		The optimal working dilution should be determined for each specific assay condition. Western blot: 1:1,000* IF: 1:1,000
Notes		*Predicted MW = 50 kDa
Storage		Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C.
References		Dozier JH, Hiser L, Davis JA, Thomas NS, Tucci MA, Benghuzzi HA, Frankfurter A, Correia JJ, Lobert S. Class II tubulin predominates in normal and tumor breast tissues. Breast Cancer Res 5:R157-R169, 2003. Moody SA, Miller V, Spano A, Frankfurter A. Developmental expression of a neuron-specific β-tubulin in frog (Xenopus laevis): A marker for growing axons during the embryonic period. J Comp Neuro 364: 219-230, 1996.
Warranty/Conditions		Covance products may not be resold or modified for resale without prior written approval.
Rev. Date		9/5/2007