人肝素结合表皮生长因子ELISA试剂盒 英文名称: Human HBEGF ELISA Kit | |
型号:null 产品货号: EK0770 | |
价格:请致电:010-57128832,18610462672 | |
品牌: 美国 | |
产品:人肝素结合表皮生长因子ELISA试剂盒 货号:EK0770 Description HBEGF (Heparin-binding EGF-like growthFactor), also known as HEGFL or DTR, is a member of the EGFFamily of proteins that in humans is encoded by the HBEGF gene. The HBEGF gene is assigned to chromosome 5, thus confirming its role in relation to diphtheria toxin susceptibility. HBEGF is an 87 amino acid glycoprotein and has highly regulated gene expression. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development andFunction. HBEGF binding and activation of EGF receptors plays a critical role during cardiac valve tissue development and the maintenance of normal heartFunction in adults. ScienCells human HBEGF ELISA kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Human HBEGF-specific polyclonal antibodies are pre-coated onto 8 x 12 divisible strips. The human-specific detection polyclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes to yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of human HBEGF in the sample that is captured on the strips. Product Use This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. Storage Store at 4°C For Frequent use, at -20°C For infrequent use. Avoid multiple Freeze-thaw cycles. Shipping Shipped on gel ice Reference 1. Nanba D, Higashiyama S (February 2004). "Dual intracellular signaling by proteolytic cleavage of membrane-anchored heparin-binding EGF-like growthFactor". Cytokine GrowthFactor Rev. 15 (1): 13-9. 2. Jin K, Mao XO, Sun Y, Xie L, Jin L, Nishi E, Klagsbrun M, Greenberg DA (July 2002). "Heparin-binding epidermal growthFactor-like growthFactor: hypoxia-inducible expression in vitro and stimulation of neurogenesis in vitro and in vivo". J. Neurosci. 22 (13): 5365-73. 3.Fen, Z., Dhadly, M. S., Yoshizumi, M., Hilkert, R. J., Quertermous, T., Eddy, R. L., Shows, T. B., Lee, M.-E. Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growthFactor-like growthFactor/diphtheria toxin receptor. Biochemistry 32: 7932-7938, 1993. 如需要其他产品资料请发邮件至wwwfudan@163.com索取
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