Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free 产品描述 Recombinant, bovine aprotinin supplied without animal-derived components. Aprotinin is a competitive, reversible inhibitor of proteolytic and esterolytic activity. A relatively heat- and acid-stable serine protease inhibitor. Forms a tight complex, blocking the active site of the enzyme. Effective at concentrations equimolar with protease. Inhibits several proteases, including coagulation factors in the prephase of blood clotting, tissue and leukocytic proteinases, chymotrypsin, trypsin (Kd = 5 x 10-14 M), plasmin (Kd = 2.3 x 10-10 M), and kallikrein (Kd = 1 x 10-7 M). Proteases not inhibited by aprotinin include Factor Xa, thrombin, pepsin, papain, and carboxypeptidases A and B. Useful for protein purification and for extending the life of cells in culture by preventing proteolytic damage. Product information | Form | Clear, colorless to amber liquid | Formulation | In 0.9 NaCl. Contains no animal-derived components. | Primary Target | chymotrypsin | Secondary target | kallikrein, plasmin, tissue and leukocytic proteinases, and trypsin | Molar mass | 6512 | Specific activity | >5 TIU/mg protein | Unit definition | One TIU (Trypsin Inhibitory Unit) is defined as the amount of aprotinin or product or inhibitor that will decrease the activity of 2 trypsin units by 50 where one trypsin unit will hydrolyze 1 µmol BAPNA per min at 25°C, pH 7.8. | Purity | ≥95 by SDS-PAGE | Chemical formula | C284H432N84O79S7 | EC number | 2329949 | RTECS | YN5080000 | CAS number | 9087-70-1 | Merck USA index | 14, 757 |
Store and ship information | | Storage | +2°C to +8°C | Ship | Blue or Dry Ice Standard Handling |
其他相关产品： 白酶抑制剂 | 目录号 | 靶蛋白酶及抑制机理 | 规 格 | 目录价(RMB) | AEBSF,Hydrochloride | 101500 | 水溶性，无毒的PMSF替代物，丝氨酸蛋白酶的不可 逆性抑制剂（与活性中心共价结合）。抑制糜蛋白酶、激肽释放酶、纤维蛋白溶酶、胰蛋白酶等。 | 50mg 100mg 500mg 1g | 588.8 960 3635.2 6924.8 | Aprotinin,Bovine Lung | 616370 | 丝氨酸蛋白酶抑制剂，能可逆的竞争性抑制蛋白水解活性及酯水解活性。在细胞培养中，能延长细胞寿命，防止细胞发生蛋白水解性损伤。 | 10mg 20mg 100mg | 704 1164.8 4416 | Aprotinin,Recombinant | 616371 | 丝氨酸蛋白酶抑制剂，能可逆的竞争性抑制蛋白水解活性及酯水解活性。在细胞培养中，能延长细胞寿命，防止细胞发生蛋白水解性损伤。 | 1mg 5mg 25mg | 742.4 1024 2060.8 | Bestatin | 200484 | 与细胞表面结合抑制细胞表面的氨基肽酶，特别是氨基肽酶B和亮氨酸氨(基)肽酶。活化巨噬细胞和T淋巴细胞，还有抗肿瘤的特性。 | 10mg | 1561.6 | E-64 Protease Inhibitor | 324890 | 不可逆的半胱氨酸蛋白酶抑制剂，且不会对其它蛋白的半胱氨酸残基起作用。 | 1mg 5mg 25mg | 499.2 1984 7500.8 | EDTA,Disodium Salt | 324503 | 可逆的金属蛋白酶抑制剂，作为螯合剂还会干扰其它金属离子依赖性的生物学反应。 | 100g 1kg | 460.8 1676.8 | Leupeptin,Hemisulfate | 108975 | 胰蛋白酶样及半胱氨酸蛋白酶的可逆性抑制剂，包括内蛋白酶Lys-C、番木瓜(蛋白)酶、组织蛋白酶B、胰蛋白酶、激肽释放酶、凝血酶等。 | 5mg 10mg 25mg 50mg 100mg | 691.2 1024 2009.6 3520 5811.2 | Pepstatin A | 516481 | 天冬氨酸蛋白酶的可逆性抑制剂，抑制组织蛋白酶D、组织蛋白酶G、胃蛋白酶、血管紧张肽原酶等。 | 5mg 25mg 100mg | 563.2 1676.8 4915.2 |
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