Aprotinin, Bovine Lung, Crystalline 产品描述 A competitive and reversible inhibitor of esterases and proteases. Forms a tight complex with and blocks the active site of the enzymes. Inhibits a number of different proteases, including chymotrypsin, coagulation factors involved in the prephase of blood clotting, kallikrein (Kd = 1 x 10-7 M), plasmin (Kd = 2.3 x 10-10 M) , tissue and leukocytic proteinases, and trypsin (Kd = 5 x 10-14 M). Does not inhibit Factor Xa and thrombin. It is relatively acid- and heat-stable. Useful as a serine protease inhibitor during purification of proteins and in studies of zymogen activation systems. Effectively inhibits target proteases at equimolar concentration. Note: 1 K.I.U. = 0.025 antiplasmin units (APU) or 0.0031 trypsin inhibitor units. Product information | Form | White to off-white crystalline solid | Primary Target | chymotrypsin | Secondary target | kallikrein, plasmin, tissue and leukocytic proteinases, and trypsin | Molar mass | 6512 | Hygrocopic | Yes | Reversible | Yes | Unit definition | One Kallikrein Inhibitory Unit (K.I.U.) is defined as the quantity of protease inhibitor that will inhibit two kallikrein units by 50 under optimal conditions. Note: 1 KIU = 0.025 antiplasmin units (APU) or 0.0031 trypsin inhibitor units. | Activity | ≥5500 KIU/mg dry weight | Purity | ≥95 by gel filtration | Contaminants | endotoxin: ≤10 EU/mg | pH value | optimum 5 - 7 | PI | 10.5 | Solubility | H2O | RTECS | YN5080000 | CAS number | 9087-70-1 | Merck USA index | 14, 757 |
Store and ship information | | Storage | +2°C to +8°C | Ship | Ambient Temperature Only Standard Handling |
其他相关产品： 白酶抑制剂 | 目录号 | 靶蛋白酶及抑制机理 | 规 格 | 目录价(RMB) | AEBSF,Hydrochloride | 101500 | 水溶性，无毒的PMSF替代物，丝氨酸蛋白酶的不可 逆性抑制剂（与活性中心共价结合）。抑制糜蛋白酶、激肽释放酶、纤维蛋白溶酶、胰蛋白酶等。 | 50mg 100mg 500mg 1g | 588.8 960 3635.2 6924.8 | Aprotinin,Bovine Lung | 616370 | 丝氨酸蛋白酶抑制剂，能可逆的竞争性抑制蛋白水解活性及酯水解活性。在细胞培养中，能延长细胞寿命，防止细胞发生蛋白水解性损伤。 | 10mg 20mg 100mg | 704 1164.8 4416 | Aprotinin,Recombinant | 616371 | 丝氨酸蛋白酶抑制剂，能可逆的竞争性抑制蛋白水解活性及酯水解活性。在细胞培养中，能延长细胞寿命，防止细胞发生蛋白水解性损伤。 | 1mg 5mg 25mg | 742.4 1024 2060.8 | Bestatin | 200484 | 与细胞表面结合抑制细胞表面的氨基肽酶，特别是氨基肽酶B和亮氨酸氨(基)肽酶。活化巨噬细胞和T淋巴细胞，还有抗肿瘤的特性。 | 10mg | 1561.6 | E-64 Protease Inhibitor | 324890 | 不可逆的半胱氨酸蛋白酶抑制剂，且不会对其它蛋白的半胱氨酸残基起作用。 | 1mg 5mg 25mg | 499.2 1984 7500.8 | EDTA,Disodium Salt | 324503 | 可逆的金属蛋白酶抑制剂，作为螯合剂还会干扰其它金属离子依赖性的生物学反应。 | 100g 1kg | 460.8 1676.8 | Leupeptin,Hemisulfate | 108975 | 胰蛋白酶样及半胱氨酸蛋白酶的可逆性抑制剂，包括内蛋白酶Lys-C、番木瓜(蛋白)酶、组织蛋白酶B、胰蛋白酶、激肽释放酶、凝血酶等。 | 5mg 10mg 25mg 50mg 100mg | 691.2 1024 2009.6 3520 5811.2 | Pepstatin A | 516481 | 天冬氨酸蛋白酶的可逆性抑制剂，抑制组织蛋白酶D、组织蛋白酶G、胃蛋白酶、血管紧张肽原酶等。 | 5mg 25mg 100mg | 563.2 1676.8 4915.2 |
|