- Product Description:
- Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 4 (PSMA4), transcript variant 2, mRNA
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001102667
- Note:
- Position of the Chimera RNAi.
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 - Gene Alias:
- HC9,HsT17706,MGC111191,MGC12467,MGC24813,PSC9
- Gene Description:
- proteasome (prosome, macropain) subunit, alpha type, 4
- Gene Summary:
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- macropain subunit C9,multicatalytic endopeptidase complex subunit C9,proteasome alpha 4 subunit,proteasome component C9,proteasome subunit HC9,proteasome subunit L
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