- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulation Status:
- For research use only (RUO)
- Fluorescent In Situ Hybridization (Cell)
- Gene Alias:
- C-C,C-C-CKR-1,CD128,CD181,CDw128a,CKR-1,CMKAR1,IL8R1,IL8RA,IL8RBA
- Gene Description:
- chemokine (C-X-C motif) receptor 1
- Gene Summary:
- The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
- Other Designations:
- receptor,alpha,interleukin-8 receptor type 1,interleukin-8 receptor type A
- Gene Alias:
- CD182,CDw128b,CMKAR2,IL8R2,IL8RA,IL8RB
- Gene Description:
- chemokine (C-X-C motif) receptor 2
- Gene Summary:
- The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
- Other Designations:
- C-X-C chemokine receptor type 2,CXC-R2,CXCR-2,CXCR2 gene for IL8 receptor type B,GRO/MGSA receptor,IL-8 receptor type 2,IL-8R B,chemokine (CXC) receptor 2,high affinity interleukin-8 receptor B,interleukin 8 receptor B,interleukin 8 receptor type 2,interl
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