Anti-EGFR (E746-A750)del Mouse Monoclonal Antibody
英文名称：  Anti-EGFR (E746-A750)del Mouse Monoclonal Antibody
型号:null    抗体货号： 26235
价格:请致电：010-57128832,18610462672
品牌: 美国    产品商标: neweastbio

EGFR (E746-A750)del [26235]
[100ul]		  

Catalog Number:  26235
Gene Symbol:  EGFR/HER1/ERBB1
Description:   Anti-EGFR (E746-A750)del Mouse Monoclonal Antibody
Background:   EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR).
Immunogen:   A synthetic peptide from the internal region of EGFR which includes the deletion of E746-A750, human origin.
Applications:   ELISA, WB
Recommended Dilutions:   
ELISA: 1:1000-1:5000
WB: 1:500-1:1000
Concentration:   1 mg/ml
Host:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes EGFR (E746-A750), but not wild type EGFR of vertebrates.
Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
 
Western blot:  

 

Western blot analysis of recombinant EGFR (E746-A750) and wildtype proteins. Purified His-tagged EGFR (E746-A750)del protein (aa 702-987) and wild-type protein (aa 702-987) were blotted with anti- EGFR (E746-A750)del mouse antibody (Cat. #26235).