| Catalog Number: 21156 |
| Gene Symbol: RAP1B |
| Description: Anti-Rap1B Rabbit Polyclonal Antibody |
| Background: Small GTPases are a super-family of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and adhesion mechanisms. Rap1 (Ras-proximate-1) regulates apoptosis through interaction with two MAP3K effectors of the MEK/ERK MAP-kinase pathway, Raf-1 and B-Raf. Rap1 regulates cell adhesion mechanisms through effector molecules such as the integrins and cadherins. |
| Immunogen: Purified His-tagged Rap1B protein. |
| Applications: ELISA, WB, IHC,IP |
Recommended Dilutions:
ELISA: 1:100-1:5000
WB: 1:100-1:1000
IHC: 1:100-1:1000 |
| Concentration: 0.2 mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purified from serum |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-Rap1B antibody recognizes Rap1B proteins from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Download Datasheet: |
| Immunoprecipitation/Western blot: |
