| Catalog Number: 21218 |
| Gene Symbol: GRB7 |
| Description: Anti-GRB7 Rabbit Polyclonal Antibody |
| Background: Grb7 is an adaptor protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. It plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Grb7 gene is commonly co-amplified (present in excess copies) in breast cancers. Grb7 is over-expressed in testicular germ cell tumors, esophageal cancers, and gastric cancers. There are clues that it involved in cell migration and metastatic progression of human esophageal carcinomas. |
| Immunogen: A synthetic peptide from the C-terminus of GRB7 protein, human origin. |
| Applications: ELISA, WB, IHC |
Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:250-1:1000
IHC: 1:50-1:100 |
| Concentration: 0.5 mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purified from serum |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-GRB7 rabbit polyclonal antibody recognizes GRB7 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles. |
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| Western blot: |
