Anti-STK11 Rabbit Polyclonal Antibody
英文名称: Anti-STK11 Rabbit Polyclonal Antibody
型号:null    抗体货号: 21281
价格:请致电:010-57128832,18610462672
品牌: 美国    产品商标: neweastbio

 

STK11 [21281]
[100 µL]
 

Catalog Number:  21281
Gene Symbol:   STK11, LKB1, PJS, hLKB1
Description:    Anti-STK11 Rabbit Polyclonal Antibody
Background:   Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer.
Immunogen:   Purified STK11 protein, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000 
WB: 1:100-1:1000 
IHC: 1:50-1:200
Concentration:    0.5mg/ml
Host:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Isotype:   
Purity:   Purified from serum
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes STK11 of vertebrates.
Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
 
Western blot:  
Western blot analysis of recombinant STK11 protein. Purified His-tagged STK11 protein was blotted with anti-STK11 rabbit polyclonal antibody (Cat. #21281).
Immunohistochemistry:  
Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue with anti-STK11 polyclonal antibody (Cat. #21281). Tissue samples were fixed with formaldehyde and blocked with 1% serum for 15 min at 37 °C. Antigen retrieval was by heat mediation in citrate buffer (pH6). Samples were then incubated with primary antibody (1:50 dilution) overnight at 4°C. A HRP-conjugated Goat anti-mouse IgG (1:50 dilution) was used as secondary antibody.