| Catalog Number: 21202 |
| Gene Symbol: ERBB2/HER2/Neu |
| Description: Anti-ErbB2 Rabbit Polyclonal Antibody |
| Background: The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22). HER2 proteins have been shown to form clusters in cell membranes that may play a role in tumorigenesis. |
| Immunogen: A synthetic peptide from the central of ErbB2 protein. |
| Applications: ELISA, WB, IHC |
Recommended Dilutions:
ELISA: 1:500-1:5000
WB: 1:200-1:2000
IHC: 1:20-1:200 |
| Concentration: 0.2 mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purified from serum |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes ErbB2 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles. |
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| Western blot: |
