Anti-IDH1 Rabbit Polyclonal Antibody
英文名称: Anti-IDH1 Rabbit Polyclonal Antibody
型号:null    抗体货号: 21277
价格:请致电:010-57128832,18610462672
品牌: 美国    产品商标: neweastbio

 

IDH1 [21277]
[100 µL]
 

Catalog Number:  21277
Gene Symbol:   IDH1
Description:   Anti-IDH1 Rabbit Polyclonal Antibody
Background:    Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.
Immunogen:   Recombinant protein of human IDH1 (amino acids 1-240).
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000 
WB: 1:1000-1:5000 
IHC: 1:50-1:500
Concentration:    1 mg/ml
Host:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Isotype:   
Purity:   Purified from serum
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-IDH1 antibody recognizes IDH1 of vertebrates.
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles.
 
Western blot:  
Western blot analysis of recombinant IDH1 protein. Purified His-tagged IDH1 protein (amino acids 1-240) (Cat. #10198) was blotted with anti-IDH1 rabbit polyclonal antibody (Cat. # 21277).