Ginsenoside Rb1 Biological Activity
IC50 Value & Target: 
In Vitro:  Rb1 inhibited melanogenesis in α-melanocyte-stimulating hormone (α-MSH) -stimulated B16 cells in a dose-dependent manner, which collectively indicated that Rb1 may have skin-whitening effects and may be formulated into skin-whitening products for skin care [1]. 
In Vivo: Application of 0.56mg of ginsenoside Rb1 resulted in significant decrement of scar elevation index, in comparison with control and lower dosage groups, furthermore achieved broader and randomly arranged collagen fibers resembling findings in normal dermis. Ginsenoside Rb1 concentration inversely correlated with the mRNA expression and immunohistochemical reactivity of scar related factors; MMP2, TIMP1, α- SMA, and TGF-β1 [2]. Ginsenoside Rb1 treatment...
 

 
Dave Gao
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