New Spectra/Por® Tube-A-Lyzer®
Disposable & Ready-to-Use Dynamic-Dialysis Device
Spectrum's Tube-A-Lyzer is a ready-to-use, gentle separation device that combines convenience and disposability with the efficiency of dynamic dialysis to significantly increase the mass transfer rate and reduce the overall dialysis from 1-2 days to 4-8 hours. This self-contained, disposable device incorporates a semi-permeable membrane tubing that separates the sample chamber from the surrounding flow-through buffer chamber. The dry Biotech Grade Cellulose Ester (CE) membrane tubing is available in 6 MWCO's and the membrane-defined sample chamber is available in 2 volume sizes. The sample port provides easy access for loading, recovering and in-process testing. The housing is designed to be a flow-through dialysate chamber that can be connected to a buffer source and a waste collection vessel, or for discharging directly to drain.

Tube-A-Lyzer is non-pyrogenic and can be sterilized (25 kGy gamma irradiation).

Mounted onto the support rack of the KrosFlo® Research I Pump System, Spectrum Laboratories part no. ACR1-U1S-01N (100 RPM) or ACR1-U2S-01N (600 RPM), the Tube-A-Lyzer device can be operated as a single unit or in parallel when multiple units are combined using a coupling bracket (sold separately) into a multi-unit device. A second pump head can be mounted to the pump to operate two Tube-A-Lyzer units in parallel.

ADVANTAGES OF DYNAMIC DIALYSIS

• Faster dialysis; reduced from 1-2 days to 4-12 hrs
• Ready-to-Use and disposable: no preparation required
• Easy sample loading, in-process testing and recovery
• Maintains maximum concentration gradient
• Prevents polarization and membrane fouling
• Achieves higher sample purities
• No heavy metals & sulfide contaminants
• 95-98% Recovery

 

Features:
CE Membrane	6 MWCO's (0.1-0.5, 3.5-5, 8-10, 20, 50 & 100 kD) Dry packaged with 20% glycerin
Sample Chamber	2 Volume sizes (8-10 ml & 25-30 ml) Biotech Grade Cellulose Ester (CE) Membrane Polycarbonate top and bottom piece Polyurethane potting Female Luer-lok sample port Polypropylene male Luer-lok cap
Buffer Chamber	Polycarbonate housing Polycarbonate end caps 5 mm (3/16 inch) hose-barb inlet / outlet ports
Dynamic Pump Rate	10-20 ml/min (should be optimized for application)

 

Dimensions:
Sample Chamber Volume	Buffer Chamber Volume	Total Length	Total Dia.	Membrane Effective Length	Membrane Dia.
8-10 ml	50-55 ml	23 cm	2.2 cm	14-16 cm	1.0 cm
25-30 ml	120-130 ml	50 cm	2.2 cm	36-38 cm	1.0 cm

Ordering Information: Spectra/Por Tube-A-Lyzer
	MWCO	Sample Volume		QTY
		8-10 ml	25-30 ml
CE	0.1-0.5 kD	137002	137042	3/pkg
	3.5-5 kD	137004	137044
	8-10 kD	137006	137046
	20 kD	137008	137048
	50 kD	137009	137049
	100 kD	137010	137050

 

Ordering Information: Tube-A-Lyzer Accessories
Part No.	Description
137100	Tube-A-Lyzer Sample Loading Kit (incl. 3 syringes (30cc), 3 dispensing tips & 2 coupling brackets)
137110	Replacement Dispensing Tips, 12/pkg
ACTU-E16-25N	Extended Life Silicone Tubing, 1/8 in. (3.1 mm) ID, 25 ft (7.6 m)

 

 

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