Anti-Active Rab7 Mouse Monoclonal Antibody
英文名称：  Anti-Active Rab7 Mouse Monoclonal Antibody
型号:null    抗体货号： 26923
价格:请致电：010-57128832,18610462672
品牌: 美国    产品商标: neweastbio

Active Rab7-GTP [26923]
[30 µL]		  

Catalog Number:  26923
Gene Symbol:  RAB7
Description:   Anti-Active Rab7 Mouse Monoclonal Antibody
Background:   Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the maturation of phagosomes.
Immunogen:   Recombinant full length protein of active Rab7
Applications:   IP, IHC, IF
Recommended Dilutions:   
1 µg for ~2 mg total cellular proteins for IP
1:100 dilution for IHC, IF
Concentration:   1 mg/ml
Host:   mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-active Rab7 antibody recognizes active Rab7 proteins of vertebrates.
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
 
Immunoprecipitation/Western blot:  
Rab7 activation assay. Purified full-length Rab7 proteins were immunoprecipitated after treated with GDP (lane 1) orGTPγS (lane 2). Immunoprecipitation was done with the anti-active Rab7 monoclonal antibody (Cat. No. 26923). Immunoblot was with an anti-Rab7 polyclonal antibody (Cat. No. 21069).
 
Related Products
Catalog# Name Size Price DataSheet
82501 Rab7 Activation Assay Kit  20 assays  $637   
26923 Active Rab7-GTP Monoclonal Antibody  30 μL  $495   
21069 Anti-Rab7A Rabbit Polyclonal Antibody  100 μL  $219   

 

Publications:
1.  VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
    Hepatology Volume 61, Issue 1, pages 361–374, January 2015
2.  Rab5 Activity Regulates GLUT4 Sorting into ***-Responsive and Non-***-Responsive Endosomal Compartments: A Potential Mechanism for Development of *** Resistance
    Endocrinology. 2014 Sep;155(9):3315-28