Acetylation is an important modification of proteins in cell biology. Acetylation occurs in thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport. Among these proteins, chromatin proteins and metabolic enzymes are highly represented, indicating that acetylation has a considerable impact on gene expression and metabolism. This antibody is a pan anti-acetylated lysine polyclonal antibody purified with acetylated lysine affinity chromatography. It specifically recognizes proteins with acetyl lysine residues. It works well in Western blotting and Immunoprecipitation, which makes it especially useful in systematically proteomic screening.
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