Taurine,牛磺酸/β-氨基乙磺酸抗体

产品编号HZ-4560R
英文名称Taurine
中文名称牛磺酸/β-氨基乙磺酸抗体
别 名2 aminoethanesulfonic acid; Taurine.
说 明 书0.1ml 0.2ml
产品类型药物与化合物抗体
研究领域心血管 细胞生物 免疫学 神经生物学 药物及化合物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Taurine
Taurine,牛磺酸/β-氨基乙磺酸抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated to Taurine
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Taurine,牛磺酸/β-氨基乙磺酸抗体PubMedPubMed
产品介绍background:
Taurine is conjugated via its amino terminal group with the bile acids chenodeoxycholic acid and cholic acid to form the bile salts sodium taurochenodeoxycholate and sodium taurocholate. The low pKa (1.5) of taurine's sulfonic acid group ensures that this moiety is negatively charged in the pH ranges normally found in the intestinal tract and thus improves the surfactant properties of the cholic acid conjugate. Taurine has also been implicated in a wide array of other physiological phenomena including inhibitory neurotransmission, long-term potentiation in the striatum/hippocampus, membrane stabilization, feedback inhibition of neutrophil/macrophage respiratory bursts, adipose tissue regulation and calcium homeostasis. The evidence for these claims, when compared against that reported for taurine's role in bile acid synthesis and osmoregulation, is relatively poor. Premature born infants who lack the enzymes needed to convert cystathione to cysteine may become deficient in taurine. Thus, taurine is a dietary essential nutrient in these individuals. Many therapeutic applications of taurine have been investigated. Some conditions that taurine might be useful in treating include: cardiovascular diseases, hypercholesterolemia, epilepsy and other seizure disorders, macular degeneration, Alzheimer's disease, hepatic disorders, alcoholism, and cystic fibrosis. Recent studies show that taurine supplements taken by mice on a high-fat diet reduced their overall weight. Studies have yet to be done on the effect of taurine on obesity in humans.

CAS:
107-35-7

Taurine,牛磺酸/β-氨基乙磺酸抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.